Synthesis of 5′-O-Aminothymidine and 5′-Deoxy-5′-Hydrazinothymidine, Novel Nucleoside Derivatives: Nucleosides and Nucleotides: Vol 4, No 3

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Abstract

Two novel nucleoside derivatives,5′-0-aminothymidine and 5′-deoxy-5′-hydrazinothymidine were synthesised as potential thymidine kinase inhibitors. The former was made from N-hydroxyu re thane and 5′-0-tosylthymidine and the latter from benzyl carbazate and 5′-0-tosylthymidine.

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Synthesis of 5′-O-Aminothymidine and 5′-Deoxy-5′-Hydrazinothymidine, Novel Nucleoside Derivatives

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Synthesis of 5′-O-Aminothymidine and 5′-Deoxy-5′-Hydrazinothymidine, Novel Nucleoside Derivatives

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