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Nucleosides and Nucleotides Volume 4, 1985 - Issue 1-2
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The Synthesis and Base-Pairing Properties of 2-Deoxy-7-deazanebularine

J. Jiricny Friedrich Miescher Institut, PO Box 2543, CH-4002, Basel
,
A. Ubasawa Friedrich Miescher Institut, PO Box 2543, CH-4002, Basel
&
S. Wood Friedrich Miescher Institut, PO Box 2543, CH-4002, Basel
Page 273 | Published online: 19 Dec 2006
 
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Abstract

2-Deoxy-7-deazanebularine-5-triphosphate (dDNTP) was used as a substrate for DNA polymerase. It was found to be an effective substitute for dATP, but not for dGTP, under standard conditions of in vitro primer extension reactions.

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