Advanced search
Publication Cover
Nucleosides and Nucleotides Volume 4, 1985 - Issue 5
Journal homepage
55
Views
11
CrossRef citations to date
0
Altmetric
Original Articles

Synthesis and biological activities of 2-Pyrimidinone Nucleosides. III.1,2 5-Alkynyl-2-Pyrimidinone 2′-Deoxyribosides

Simon M.N. Efange Department of Medicinal Chemistry, State University of New York at Buffalo, Amherst, N.Y., 14260
,
Yung-Chi Cheng Department of Pharmacology, University of North Carolina, North Carolina Chapel Hill, 27514
&
Thomas J. Bardos Department of Medicinal Chemistry, State University of New York at Buffalo, Amherst, N.Y., 14260
Pages 545-564 | Received 21 Jan 1985, Published online: 03 Jan 2007
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

The syntheses of 5-ethynyl-, 5-phenylethynyl- and 5-propynyl-2(1H)-pyrimidinone 2′-deoxyribosides are described. Two of the new nucleosides, 14 a and 14 c, showed significant antiviral activities against HSV-1 and HSV-2 in tissue culture.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.