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Original Articles

Synthesis of Chiral 1′,2′-SECO-Nucleosides OF Guanine AND Uracil

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Pages 201-211 | Received 05 Apr 1988, Published online: 24 Oct 2006
 

Abstract

2R-Chloromethoxy-1, 3S-dibenzyloxybutane (6a) and 2R-chloro methoxy-1, 3S,4-tribenzyloxybutane (6b) chirons readily available from D-isoascorbic acid, were used in the preparation of 1′,2′-seco-nucleo-sides of uracil and guanine.

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