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Nucleosides and Nucleotides Volume 8, 1989 - Issue 3
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Original Articles

The Acidic Hydrolysis of Nucleosides and Nucleotides

Ewa Zielonacka-lis Institute of Bioorganic Chemistry Polish Academy of Sciences Poznań, Noskowskiego, 12/14, Poland
Pages 383-405 | Received 15 Dec 1987, Published online: 24 Oct 2006
 
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Abstract

The influence of sugar and base substitutions on the stability of the N-glycosidic bond of nucleosides in acidic medium is examined in detail. Then the mechanistic aspect of the phenomenon is described. The last part is devoted to the acidic hydrolysis of nucleotides.

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