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Nucleosides and Nucleotides Volume 8, 1989 - Issue 5-6
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PLENARY LECTURES

Membrane Transport of Nucleoside Analogues in Mammalian Cells

Thomas P. Zimmerman Experimental Therapy Division, Wellcome Research Laboratories Research, Triangle Park, North Carolina, 27709
,
Barbara A. Domin Experimental Therapy Division, Wellcome Research Laboratories Research, Triangle Park, North Carolina, 27709
,
William B. Mahony Experimental Therapy Division, Wellcome Research Laboratories Research, Triangle Park, North Carolina, 27709
&
Karen L. Prus Experimental Therapy Division, Wellcome Research Laboratories Research, Triangle Park, North Carolina, 27709
Pages 765-774 | Published online: 24 Oct 2006
 
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Abstract

This paper attempts to summarize what is known, from rapid kinetic studies of cell membrane transport, about the mechanism by which nucleoside analogues permeate the plasma membrane of mammalian cells.

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