Abstract
2′,3′-Dideoxy-3′-isothiocyano, -isocyano, and -isoselenocyanothymidines (6b, 8b, and 9) were synthesized from the corresponding 3′-amino derivatives (5a, b). These nucleosides were tested for inhibitory activity of the pathogenicity of HIV-1 and the growth inhibitory activity of mouse and human cancer cell lines.