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Nucleosides and Nucleotides Volume 10, 1991 - Issue 5
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Effects of Adenosine (ADO) and A1 and A2 Ado Agonists on Calcium Uptake and cAMP Levels in Cultured Rat Mesangial Cells (MC)

A. Olivera Laboratorio de Fisiopatologia Renal. Fundación Jimenez Díaz - C.S.I.C., Avda Reyes Católicos 2, 28040, Madrid, SPAIN
,
M. Tomás Laboratorio de Fisiopatologia Renal. Fundación Jimenez Díaz - C.S.I.C., Avda Reyes Católicos 2, 28040, Madrid, SPAIN
&
J. M. López-Novoa Laboratorio de Fisiopatologia Renal. Fundación Jimenez Díaz - C.S.I.C., Avda Reyes Católicos 2, 28040, Madrid, SPAIN
Pages 1169-1171 | Published online: 04 Oct 2006
 
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Abstract

MC exhibits A1 and A2 receptors with opposite actions on cAMP formation and 45Ca2+ uptake. ADO 10−4 M activated both second messengers, but neither A1 nor A2 receptors seem to be involved in these ADO-induced effects.

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