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Nucleosides and Nucleotides Volume 10, 1991 - Issue 5
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Adenosine-induced dilation of rat thoracic aorta is mediated by cyclic GMP and is age-dependent

Hideki Moritoki Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi, Tokushima, 770, Japan
,
Tetsuhiro Hisayama And Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi, Tokushima, 770, Japan
&
Haruyasu Ueda Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi, Tokushima, 770, Japan
Pages 1231-1233 | Published online: 04 Oct 2006
 
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Abstract

Contrary to the established concept that the effects of adenosine are mediated by CAMP, we found that the vasodilator effect of adenosine is in part mediated by cGMP, and decreased with age.

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