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Original Articles

SYNTHESIS OF CYCLIC DINUCLEOTIDES BY AN H-PHOSPHONATE METHOD IN SOLUTION

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Pages 1679-1686 | Received 31 May 1996, Accepted 31 Jul 1996, Published online: 22 Aug 2006
 

Abstract

We report synthesis of each of the ten cyclic 2′-deoxyribodinucleotides by a solution-phase H-phosphonate method. The cyclic dimers have been characterized by 31P NMR, MS, UV, and enzymatic degradation.

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