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Original Articles

Recent Developments in Mass Spectrometry: Rna Sequencing

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Pages 573-577 | Published online: 22 Aug 2006
 

Abstract

Simplified sequencing of an oligoribonucleotide containing 16 bases is accomplished by matrix assisted laser desorptiodionization time of flight (MALDI-TOF) mass spectrometry. We used delayed ion extraction (DE) technique and kinetic degradation with two exonucleases.

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