Multiple Sequence Elements Involved in Polyadenylation at The Murine Igm Secretory Poly(A)Site.: Nucleosides and Nucleotides: Vol 16, No 5-6

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Abstract

We show that the mouse immunoglobulin (IgM) secretory poly(A) site contains an extended hexanucleotide sequence element and two downstream elements spanning GU-rich regions which all contribute to polyadenylation efficiency. The multiple elements may provide a flexibility to accommodate changes during the regulation of polyadenylation.

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Multiple Sequence Elements Involved in Polyadenylation at The Murine Igm Secretory Poly(A)Site.

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Multiple Sequence Elements Involved in Polyadenylation at The Murine Igm Secretory Poly(A)Site.

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