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Nucleosides and Nucleotides Volume 17, 1998 - Issue 9-11
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Original Articles

Pna Array Technology in Molecular Diagnostics

Albert Geiger PNA Diagnostics A/S, Ronnegade 2, DK-21OO, Copenhagen Ø, Denmark
,
Ane Lester PNA Diagnostics A/S, Ronnegade 2, DK-21OO, Copenhagen Ø, Denmark
,
Jörg Kleiber Boehringer Mannheim GmbH, Molecular Diagnostics, D-82377, Penzberg, Germany
&
Henrik Ørum PNA Diagnostics A/S, Ronnegade 2, DK-21OO, Copenhagen Ø, Denmark
Pages 1717-1724 | Published online: 22 Aug 2006
 
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Abstract

A comparative study using immobilised DNA and PNA oligomers demonstrates the suitability of PNA molecules as sequence specific capture probes in the detection of single point mutations in a DNA analyte and in the analysis of complex analyte mixtures.

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