DNA-PHONA-PNA Chimeric Molecules: Contributions to Binding Against Complementary DNA

A. Peyman* Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

E. Uhlmann Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

K. Wagner Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

S. Augustin Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

C. Weiser Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

S. Hein Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

D. Langner Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

G. Breipohl Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

D. W. Will Hoechst Marion Roussel Deutschland GmbH, D-65926, Frankfurt, Germany

show all

Abstract

The synthesis of a DNA-PHONA-PNA chimeric molecule using the Mmt protection strategy is described. The chimeric oligomer shows duplex binding properties that are comparable to PNA. Obviously, PHONA building blocks can be incorporated into PNAs without distortion of the PNA structure

Dedicated to Professor Hartmut Seliger on the occasion of his sixtieth birthday

Notes

Dedicated to Professor Hartmut Seliger on the occasion of his sixtieth birthday

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

DNA-PHONA-PNA Chimeric Molecules: Contributions to Binding Against Complementary DNA

Information for

Open access

Opportunities

Help and information

DNA-PHONA-PNA Chimeric Molecules: Contributions to Binding Against Complementary DNA

Abstract

Notes

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature