Nucleosides and Nucleotides. 165. Chemical Ligation of Oligodeoxynucleotides Having a Mercapto Group at the 5-Position Of 2′-Deoxyuridine via a Disulfide BondFootnote^#
^#This paper is dedicated to the late Professor Tsujiaki Hata.

Yoshihito Ueno Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo, 060, Japan

Aiko Nakagawa Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo, 060, Japan

Akira Matsuda Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo, 060, Japan

Abstract

We describe the nonenzymatic ligation of oligodeoxynucleotides (ODNs) containing a mercapto group at the 5-position of 2′-deoxyuridine via a disulfide bond. Two ODNs containing different sequences were efficiently ligated in the presence of a template by this method.

^#This paper is dedicated to the late Professor Tsujiaki Hata.

Notes

^#This paper is dedicated to the late Professor Tsujiaki Hata.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Nucleosides and Nucleotides. 165. Chemical Ligation of Oligodeoxynucleotides Having a Mercapto Group at the 5-Position Of 2′-Deoxyuridine via a Disulfide BondFootnote^#
^#This paper is dedicated to the late Professor Tsujiaki Hata.

Information for

Open access

Opportunities

Help and information

Nucleosides and Nucleotides. 165. Chemical Ligation of Oligodeoxynucleotides Having a Mercapto Group at the 5-Position Of 2′-Deoxyuridine via a Disulfide BondFootnote##This paper is dedicated to the late Professor Tsujiaki Hata.

Abstract

Notes

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature

Nucleosides and Nucleotides. 165. Chemical Ligation of Oligodeoxynucleotides Having a Mercapto Group at the 5-Position Of 2′-Deoxyuridine via a Disulfide BondFootnote^#
^#This paper is dedicated to the late Professor Tsujiaki Hata.