Abstract
Interaction of 2-methyl-4,6-bis-(4-N,N-dimethylaminophenyl) pyrylium salt (P2) with [d(CGACGTCG)]2 was investigated by H NMR spectroscopy. The aromatic signals of P2 and the oligomer were shifted to the upfield by forming the complex, and intermolecular NOEs were also observed between P2 and the terminal CpG base steps but not between P2 and the central CpG. These results indicate that P2 binds to the weakly stacking CpG steps in an intercalation manner.
This paper is dedicated to the memory of late Professor Tsujiaki Hata.
Notes
This paper is dedicated to the memory of late Professor Tsujiaki Hata.