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Nucleosides and Nucleotides Volume 17, 1998 - Issue 1-3
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Original Articles

Cerium(IV)/Lanthanide(III)/Dextran Ternary Solutions for Efficient and Homogeneous DNA Hydrolysis

Jun Sumaoka Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo, Tokyo, 113, JAPAN
,
Ayako Kajimura Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo, Tokyo, 113, JAPAN
,
Takamitsu Imai Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo, Tokyo, 113, JAPAN
,
Masayuki Ohno Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo, Tokyo, 113, JAPAN
&
Makoto Komiyama Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo, Tokyo, 113, JAPAN
Pages 613-623 | Published online: 22 Aug 2006
 
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Abstract

Homogeneous and neutral solutions are prepared by mixing Ce(NH4)2(NO3)6 and dextrans at pH 7. These homogeneous solutions are active for DNA hydrolysis. Still more importantly, the activities of the binary solutions are greatly promoted by the addition of various lanthanide(III) ions.

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