Trajectories and predictors of stress and depressive symptoms in spousal and intimate partner cancer caregivers

Abstract

Purpose

The objective of the study is to investigate trajectories of stress and depressive symptoms of spousal and intimate partner caregivers in the context of cancer. We also examined the patient-related predictors of caregiver stress and depression.

Design

This is a longitudinal cohort study.

Participants

Patients diagnosed with cancers affecting the hepatobiliary and pancreatic system and their spousal or intimate partner caregivers were recruited at a large tertiary cancer center.

Methods

The patients and caregivers were assessed for their level of stress, depressive symptoms, relationship quality, and quality of life at the time of the patients’ diagnosis, every 2 months for 12 months and then at 18 months.

Findings

One hundred and seventy-nine caregivers were included in the trajectory analyses. Amongst the 179 caregivers, 120 patient and caregiver dyads had complete data at baseline to 6-months. The majority of the spousal caregivers were female (84%) and the mean age was 57 years. 25% of caregivers reported high levels of chronic depressive symptoms. However, significant reductions were observed at 6 months. High and moderate levels of caregiver stress were also reported in 21% and 36% of caregivers, respectively. The caregivers who reported moderate levels of stress had a decrease in stress over time while those in the high stress group reported stable levels of stress over time. Caregivers’ stress is predicted by the cancer patients’ depressive symptoms but not patients’ quality of life.

Conclusions

Caregivers who reported high levels of stress and depressive symptoms at patients’ cancer diagnosis remain high even after the initial adjustment. A bidirectional relationship between the caregivers’ stress and the patients’ depressive symptoms was observed.

Implications

The development of dyadic interventions focusing on the patients’ and caregivers’ distress is warranted to decrease psychological morbidities of the dyad.

Keywords:

• cancer caregiver
• depression
• dyadic functioning
• stress
• quality of life

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

Funded by National Cancer Institute (NCIK07CA118576).