Cajal Bodies and Plant RNA Metabolism

Abstract

Intracellular location of components associated with RNA metabolism is a key feature of gene expression regulation, although it is often neglected in favor of more direct factors influencing expression. A number of nuclear and subnuclear compartments exist, each carrying out specific functions. This article focuses on Cajal bodies, a dynamic body composed of numerous proteins and small RNAs. Cajal bodies, or CBs, are universal entities found in both the nucleolus and nucleoplasm of most living cells. Their function relates to RNA metabolism, including transcription, splicing, stable RNA modification, small RNA biogenesis, gene silencing, nonsense-mediated decay and telomere maintenance. It is generally thought that CBs form docking stations for each of these functions so that the individual processes proceed quickly and in an organized manner. A brief introduction on what is known about the function and composition of CBs in animal cells is provided, followed by highlights of the latest research on CBs in plants.

Keywords:

• gene expression regulation
• nuclear compartmentation
• nucleolus
• RNA biogenesis and maturation
• subnuclear particles

Acknowledgments

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