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Articles

Stereotactic Body Radiation Therapy in Oligometastatic Uterine Cancer: Clinical Outcomes and Toxicity

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Pages 522-530 | Received 28 Mar 2020, Accepted 24 Aug 2020, Published online: 14 Sep 2020
 

Abstract

We report on clinical outcomes in patients with oligometastatic uterine cancer treated with stereotactic body radiation therapy (SBRT). Twenty-seven patients with 61 lesions were treated with SBRT. Median follow-up was 16.9 months. Local control was achieved in 49/61 (80.3%) lesions. One-year local-progression-free survival and overall survival were 75.9% and 65.4%. Lesions with favorable response were smaller than lesions with unfavorable response (p = .007). Liver lesions were less likely to achieve favorable response (p = .0128). There were no grade 3 or 4 events. Treatment with SBRT can provide excellent local control in oligometastatic uterine cancer with minimal toxicity.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

Author contributions

Conception and design: Abhinav V. Reddy, Matthew N. Mills, Leonid B. Reshko, Charles R. Kersh. Data analysis and interpretation: Abhinav V. Reddy, Matthew N. Mills, Leonid B. Reshko, K. Martin Richardson. Manuscript writing: Abhinav V. Reddy, Matthew N. Mills. Final approval of manuscript: Abhinav V. Reddy, Matthew N. Mills, Leonid B. Reshko, Charles R. Kersh.

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