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Brief Report

Rare Association between Sarcoidosis and Smoldering Multiple Myeloma: A Case Report

, , , &
Pages 880-884 | Received 21 Jul 2021, Accepted 29 Sep 2021, Published online: 13 Oct 2021
 

Abstract

While several case reports suggest an association between sarcoidosis and multiple myeloma (MM), few cases involve smoldering MM. We report a case of sarcoidosis and smoldering MM discovered simultaneously in a patient admitted for hypercalcemia. Initial tests raised suspicion for sarcoidosis and MM, prompting invasive testing. Surgical lung biopsy revealed necrotizing granulomas, which could represent sarcoidosis in the appropriate setting. Thus, sarcoidosis was diagnosed following a negative infectious workup. Bone marrow biopsy revealed 13% plasma cells leading to subsequent diagnosis of smoldering MM. This case demonstrates the challenge of determining disease activity when other causes of CRAB symptoms are present.

Acknowledgments

The authors thank Serena Mistry for providing .

Declaration of interest

The authors report no conflict of interest.

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