Molecular mechanism of interactions between chrysin and I-kappa-B kinase epsilon (IKKe)/tank binding kinase-1(TBK1): Cell-based assay and in silico molecular docking studies

M. Amir SiddiquiDepartment of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India;

BadruddeenDepartment of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India; Correspondence[email protected]

Juber AkhtarDepartment of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India;

Shahab Uddin M.S.Centre for Cellular and Molecular Platforms, National Centre for Biological Sciences Campus, Bangalore, Karnataka, India

Mohammad Irfan KhanDepartment of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India;

Mohammad KhalidDepartment of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India;

Abstract

Communicated by Ramaswamy H. Sarma

Acknowledgements

The authors would like to thank for the excellent technical assistance from C-CAMP, NCBS Campus, Bangalore. The authors offer their sincere thanks to the Integral University for providing technical support and internal review for this manuscript (IU/R&D/2018/MNC000282).

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The authors declare no conflict of interests related with this manuscript.

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Molecular mechanism of interactions between chrysin and I-kappa-B kinase epsilon (IKKe)/tank binding kinase-1(TBK1): Cell-based assay and in silico molecular docking studies

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Molecular mechanism of interactions between chrysin and I-kappa-B kinase epsilon (IKKe)/tank binding kinase-1(TBK1): Cell-based assay and in silico molecular docking studies

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