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Journal of Biomolecular Structure and Dynamics Volume 38, 2020 - Issue 13
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Letters to the Editor

Molecular dynamics simulations reveal the determinants of cyclin-dependent kinase 2 inhibition by 5-nitrosopyrimidine derivatives

Stefano GuglielmoDipartimento di Scienza e Tecnologia del Farmaco, Universita' degli Studi di Torino, Turin, Italy; ;Scientific Computing Competence Centre (C3S), University of Turin, Turin, Italy; Correspondence[email protected]
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Daniela CorteseDipartimento di Scienza e Tecnologia del Farmaco, Universita' degli Studi di Torino, Turin, Italy; ;Northern Institute for Cancer Research, School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, UKView further author information
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Celine CanoNorthern Institute for Cancer Research, School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, UKView further author information
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Roberta FrutteroDipartimento di Scienza e Tecnologia del Farmaco, Universita' degli Studi di Torino, Turin, Italy; View further author information
Pages 4016-4024 | Received 15 Jul 2019, Accepted 03 Sep 2019, Published online: 23 Sep 2019
 
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Abstract

Communicated by Ramaswamy H. Sarma

Acknowledgments

The authors are thankful to prof. A. Gasco for valuable discussion.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The study was supported by the University of Turin, “Ricerca Locale” under grant GUGS_RILO_17_01 and by MIUR under grant GUGS_FFABR_17_01.

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