Computational insight into the conformational transition of human toll-like receptor 8 in the agonist-induced activation processes

Shuheng HuangKey Laboratory of Biorheological Science and Technology (Ministry of Education), Chongqing University, Chongqing, China; ;College of Bioengineering, Chongqing University, Chongqing, China; View further author information

Hu MeiKey Laboratory of Biorheological Science and Technology (Ministry of Education), Chongqing University, Chongqing, China; ;College of Bioengineering, Chongqing University, Chongqing, China; Correspondence[email protected]
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Linxin ChenCollege of Bioengineering, Chongqing University, Chongqing, China; View further author information

Tingting ShiCollege of Bioengineering, Chongqing University, Chongqing, China; View further author information

Zuyin KuangCollege of Bioengineering, Chongqing University, Chongqing, China; View further author information

Yu HengCollege of Bioengineering, Chongqing University, Chongqing, China; View further author information

Yonghong ZhangMedicine Engineering Research Center, College of Pharmacy, Chongqing Medical University, Chongqing, ChinaCorrespondence[email protected]
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Laichun LuKey Laboratory of Biorheological Science and Technology (Ministry of Education), Chongqing University, Chongqing, China; ;College of Bioengineering, Chongqing University, Chongqing, China; Correspondence[email protected]
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Abstract

Communicated by Ramaswamy H. Sarma

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The authors claim no conflicts of interest.

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Funding

The authors acknowledge the support of the Fundamental Research Funds for the Central Universities (Project No. 106112017CDJQJ238816), the Graduate Scientific Research and Innovation Foundation of Chongqing (Project No. CYB19042) and the National Natural Science Foundation of China for Young Scholars (Project No. 21707012).

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Computational insight into the conformational transition of human toll-like receptor 8 in the agonist-induced activation processes

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Computational insight into the conformational transition of human toll-like receptor 8 in the agonist-induced activation processes

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