Binding efficacy of aminobenzoic acid derivatives with DNA duplex: drug binding sites and DNA structure and dynamics

P. Chanphaia Department of Chemistry-Biochemistry and Physics, University of Québec at Trois-Rivières, Trois-Rivières, Québec, CanadaView further author information

F. Cloutiera Department of Chemistry-Biochemistry and Physics, University of Québec at Trois-Rivières, Trois-Rivières, Québec, Canada;b Groupe de Recherche en Signalisation Cellulaire, University of Québec at Trois-Rivières, Trois-Rivières, Québec, CanadaView further author information

C. Reyes-Morenoc Department of Medical Biology, University of Québec at Trois-Rivières, Trois-Rivières, Québec, Canada;b Groupe de Recherche en Signalisation Cellulaire, University of Québec at Trois-Rivières, Trois-Rivières, Québec, CanadaView further author information

G. Bérubéa Department of Chemistry-Biochemistry and Physics, University of Québec at Trois-Rivières, Trois-Rivières, Québec, Canada;b Groupe de Recherche en Signalisation Cellulaire, University of Québec at Trois-Rivières, Trois-Rivières, Québec, CanadaCorrespondence[email protected]
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H. A. Tajmir-Riahia Department of Chemistry-Biochemistry and Physics, University of Québec at Trois-Rivières, Trois-Rivières, Québec, CanadaCorrespondence[email protected]
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Abstract

Communicated by Ramaswamy H. Sarma

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No potential conflict of interest was reported by the authors.

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Funding

We thank the Natural Sciences and Engineering Research Council of Canada (NSERC) for the financial support. This study was also supported by grants from the Cancer Institute of Canadian Institutes of Health Research (CIHR; number 392334), the Cancer Research Society (CRS; number 22471) and Aligo Innovation (number 150923) to C. Reyes-Moreno and G. Bérubé.

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Binding efficacy of aminobenzoic acid derivatives with DNA duplex: drug binding sites and DNA structure and dynamics

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Binding efficacy of aminobenzoic acid derivatives with DNA duplex: drug binding sites and DNA structure and dynamics

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