A commentary on the Spanish hypertension studies MAPEC and HYGIA

Björn Lemmera Institue of Pharmacology & Toxicology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Frankfurt, GermanyCorrespondence[email protected]

Martin Middekeb Hypertension Centre Munic, An Excellence Centre of the European Society of Hypertension (ESH), München, Germany

ABSTRACT

The recently published chronotherapeutic Spanish papers MAPEC and HYGIA proposing that antihypertensive drug treatment should be given at bedtime suffers from obvious deficiencies in study design and are not a valid basis for drug treatment of hypertension.

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Disclosure of interest

The authors have no conflict of interest.

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A commentary on the Spanish hypertension studies MAPEC and HYGIA

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A commentary on the Spanish hypertension studies MAPEC and HYGIA

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