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Original Article

In Vivo Patterns of Circulating Steroids in Adult Male Rats III. Effect of Total Parenteral Nutrition on the Diurnal Variation of Testosterone

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Pages 95-105 | Published online: 07 Aug 2009
 

Abstract

The in vivo pattern of circulating testosterone (T) during a 24 hr period was investigated in stock-fed and total parenterally nourished (TPN) rats. A diurnal rhythm of T was observed in control rats with highest concentrations occurring during the dark period. The loss of this rhythm in rats maintained on TPN shows that nutritional regimen affects circulating T and overrides the synchronizing effect of the light/dark cycle.

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