Proliferative Vitreoretinopathy: Pathobiology and Therapeutic Targets

Abstract

The cell biology and molecular mediators of proliferative vitreoretinopathy continue to be elucidated. The purpose of this review is to summarize contemporary findings in the visual and neurosciences relevant to the pathophysiology of proliferative vitreoretinopathy, with an emphasis on the biologic mediators that represent potential therapeutic targets.

Keywords:

• vitreoretinopathy
• proliferative/etiology/physiopathology/therapy
• intercellular signaling peptides and proteins
• retinal detachment