Post-LASIK Ectasia: Twenty Years of a Conundrum

Abstract

Corneal ectasia has emerged as a serious complication of laser vision correction (LVC) procedures since the first report by Seiler in 1998. Thereby, its prevention has become a major concern for refractive surgeons. Ectasia occurs due to biomechanical decompensation of the stroma, which may be related to a severe impact on corneal structure (i.e., attempted treatment for high myopia) or the altered biomechanical properties preoperatively. The current understanding is that a combination from those factors determines stability or ectasia progression after LVC. Abnormal corneal topography has been the most important surrogate for lower biomechanical properties, but novel imaging technologies such as tomography and biomechanical assessment have proven to enhance the ability for detecting mild ectatic disease, such as in the eyes with normal topography from patients with clinical ectasia in the fellow eye. Bohac and associates in a retrospective case series analyzed data from 30,167 eyes from 16,732 documented ten eyes (0.033%) of seven patients that developed post-LASIK ectasia. This data supports the concept that the actual incidence of ectasia has decreased from 0.66% reported by Pallikaris in 2001. This has been the result of major development related to the advanced screening strategies. Nevertheless, mysterious cases of ectasia still challenge the field and stimulated research in this field. Ocular allergy and eye rubbing may be a factor that triggered ectasia in such series. Artificial intelligence (AI) and machine-learning algorithms may play a definitive role for further enhancing ectasia risk assessment. Reporting ectasia after LVC is needed.

Keywords:

• LASIK
• ectasia
• screening
• risk
• tomography

FINANCIAL DISCLOSURE

Dr. Ambrósio is a consultant to Oculus, Alcon and Zeiss