Translating the Concept of Suppressor/Regulatory T Cells to Clinical Applications

Alessandra Franco Department of Medicine and Pediatrics, University of California San Diego, La Jolla, California, USA

Salvatore Albani Department of Medicine and Pediatrics, University of California San Diego, La Jolla, California, USA; IACOPO Institute for Translational Medicine, and Androclus Therapeutics, Inc, San Diego, California, USA www.iacopo.orgCorrespondence[email protected]

Abstract

The in vivo expansion of suppressor/regulatory T cells (Tregs) is a desirable event in autoimmunity and transplantation. Here we summarize the general rules involved in antigen recognition by T cells and describe Tregs and their requirements, discussing different levels of immune intervention.

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Translating the Concept of Suppressor/Regulatory T Cells to Clinical Applications

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Translating the Concept of Suppressor/Regulatory T Cells to Clinical Applications

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