Abstract
Background: This study assessed cancer patients' knowledge and attitudes towards clinical trials (CTs). Methods: A survey was administered to 100/141 cancer outpatients. Results: 82% respondents had heard of CTs, but many could only provide limited definitions and perceived them as high risk. About half had previously been approached to participate in a trial, and 67% had agreed to participate. Factors influencing participation in trials, barriers to recruitment, and suggestions for increased recruitment in clinical trials were identified. Conclusions: The findings suggest general support of CTs. Education programs are needed to raise awareness, reduce fears, and dispel myths about CT participation.