Impact of volume indices in bioelectrical impedance measurement on the assessment of cardiac function indices by echocardiography in hemodialysis patients

Abstract

Introduction

Cardiovascular events resulting from volume overload are a primary cause of mortality in hemodialysis patients. Bioelectrical impedance analysis (BIA) is significantly valuable for assessing the volume status of hemodialysis (HD) patients. In this article, we explore the correlation between the volume index measured by BIA and the cardiac function index assessed by echocardiography (ECG) in HD patients.

Methods

Between April and November 2018, we conducted a cross-sectional study involving randomly selected 126 maintenance HD patients. Comprehensive data on medical history and laboratory test results were collected. Subsequently, we investigated the correlation between volume indices measured by BIA and cardiac function parameters by ECG.

Results

We discovered a significant correlation between the volume indices measured by BIA and various parameter of cardiac function. The Left Ventricular Hypertrophy (LVH) group exhibited higher levels of the percentage of Extracellular Water (ECW%) and the percentage of Total Body Water (TBW%) compared to the Non-LVH group. Extracellular Water (ECW) and Third Interstitial Fluid Volume (TSFV) were identified as independent risk factors for Left Ventricular Mass (LVM), and both demonstrated a high predictive value for LVM. ECW% emerged as an independent risk factor for the Left Ventricular Mass Index (LVMI), with a high predictive value for LVMI.

Conclusion

ECW and TSFV were found to be positively associated with cardiac function parameters in HD patients.

Keywords:

• Hemodialysis
• volume indices
• bioelectrical impedance
• cardiac function
• echocardiography

Ethics approval statement

This study was reviewed along with endorsed by the Huaihai Hospital Medical Ethics Board, Xuzhou Medical University (Ethics No. 2018-007).

Patient consent statement

All selected patients had given informed consent to participate in the study.

Disclosure statement

The authors declare that there are no competing interests associated with the manuscript.

Correction Statement

This article has been corrected with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

This work was supported by Jiangsu Provincial Natural Science Foundation (BK20181150) and also supported by Key R & D plan of Xuzhou City (KC22261).