Perturbation of the enterobacterial microflora detected by molecular analysis

Abstract

The enterobacterial populations of faecal samples collected from two human subjects during a twelve-month period were studied. Analysis of the composition of the populations using ribotyping showed that Subject 1 harboured a relatively simple and stable enterobacterial population in which a single Escherichia coli strain predominated. In contrast, the enterobacterial population of Subject 2 underwent a marked change in composition, possibly associated with the administration of amoxicillin, and became dominated by multiple drug resistant E. coli and ampicillin-resistant klebsiella strains.