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Biofouling
The Journal of Bioadhesion and Biofilm Research
Volume 27, 2011 - Issue 5
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Original Articles

Development of silver-containing austenite antibacterial stainless steels for biomedical applications Part I: microstructure characteristics, mechanical properties and antibacterial mechanisms

, , , , &
Pages 449-457 | Received 18 Nov 2010, Accepted 09 Apr 2011, Published online: 19 May 2011
 

Abstract

The as-quenched (AQ) microstructure of the Ag-containing alloys was found to be essentially a mixture of austenite (γ) and Ag phases. The Ag phase precipitates had a face-centered-cubic structure and lattice parameter a = 4.09 Å. When the alloy contained Ag ≥0.2 wt%, the mechanical properties were slightly enhanced because of the precipitate strengthening by the Ag phase precipitates. Moreover, the Ag-containing alloys exhibited ductile fracture after tensile testing. The results of an antibacterial test revealed that the Ag phase precipitates play a key role in the antibacterial mechanism of Ag-containing alloys: Ag+ ions released from the Ag phase precipitates can kill bacteria. It is suggested that as AISI 316L alloy has an Ag content ≥0.2 wt%, it will have excellent antibacterial properties against both Staphylococcus aureus and Escherichia coli, with an antibacterial rate of nearly 100%.

Acknowledgements

The authors would like to thank the Center of Excellence for Clinical Trial and Research in Neurology and Neurosurgery, Taipei Medical University-Wan Fang Hospital for financially supporting this research under contract No. DOH100-TD-B-111-003, and supported partly by the Department of Health, Executive Yuan, Taiwan under contract No. DOH100-TDN-111-004. The authors would also like to thank the Taipei Medical University Hospital for financially supporting this research under contract 98TMU-TMUH-03-1.

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