Morphometric Evaluation of Tissue-Implant Reaction Associated With ALCAP and TCP Bioceramics In Vivo

Kenneth R. Butler Department of Health Science, School of Health Related Professions, University of Mississippi Medical Center, Jackson, Mississippi, USA

Hamed A. Benghuzzi Department of Health Science, School of Health Related Professions, University of Mississippi Medical Center, Jackson, Mississippi, USA

Aaron Puckett Department of Restorative Dentistry, School of Dentistry, University of Mississippi Medical Center, Jackson, Mississippi, USA

Abstract

The purpose of this investigation was to correlate the thickness of the fibrous capsule and the various histological components surrounding aluminum-calcium phosphate (ALCAP) and tricalcium phosphate (TCP) bioceramics at the subcutaneous (sc) and intraperitoneal (ip) implantation sites. The rational of conducting this investigation is to further elucidate the mechanisms of tissue-implant interaction. Thirteen Sprague-Dawley adult male albino rats were randomly divided into three groups. Animals in groups I and II (n = 5/group) were implanted at both ip and sc implantation sites with either ALCAP or TCP ceramics, respectively. Animals in group III (n

Keywords

Alcap Calcium-PHOSPHATE Ceramics Collagen Drug Delivery Systems Fibroblasts Fibrous Tissue Implants Inflammatory Response Macrophages Neutrophils Tcp

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Morphometric Evaluation of Tissue-Implant Reaction Associated With ALCAP and TCP Bioceramics In Vivo

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Morphometric Evaluation of Tissue-Implant Reaction Associated With ALCAP and TCP Bioceramics In Vivo

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