Modified Noble Plication for the Prevention of Intestinal Intussusception After Renal Transplantation in Dogs

Andrew E. Kyles Comparative Transplantation Laboratory, Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, California, USA

Clare R. Gregory Comparative Transplantation Laboratory, Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, California, USA

Stephen M. Griffey Comparative Transplantation Laboratory, Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, California, USA

Lynda Bernsteen Comparative Transplantation Laboratory, Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, California, USA

Randall E. Morris Department of Cardiovascular Surgery, Falk Cardiovascular Research Center, Stanford University School of Medicine, Stanford, California, USA

Abstract

Intestinal intussusception is a frequent problem after experimental transplantation in dogs. This report describes the safety and efficacy of performing a modified Noble plication for the prevention of intussusception. Heterotopic renal transplantation and plication was performed in 20 dogs. Dogs were killed when the serum creatinine concentration exceeded 7 mg/dL because of acute rejection (19 dogs) or venous occlusion (1 dog). Gastrointestinal signs were commonly observed, but no dog experienced an intestinal intussusception, compared to 3 of 14 dogs (21%) previously treated using a similar immunosuppressive regimen. This study supports the routine use of enteroplication in dogs undergoing renal transplantation.

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Modified Noble Plication for the Prevention of Intestinal Intussusception After Renal Transplantation in Dogs

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Modified Noble Plication for the Prevention of Intestinal Intussusception After Renal Transplantation in Dogs

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