Pressure dependence of the reversible hydrolysis of thiazolium salts

Abstract

The hydrolysis of thiazolium salts is studied under varying pressures between 0.1 and 85 MPa. Activation and reaction volumes are obtained for different reaction steps. The results confirm the reaction scheme, where the thiazolium cation forms a pseudobase by addition of an hydroxide ion. The pseudobase can be protonated or can form a ring-opened species, which can further be deprotonated.

Key Words:

• High pressure
• activation volume
• reaction volume
• thiazolium salts
• stopped-flow