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Inhalation Toxicology
International Forum for Respiratory Research
Volume 15, 2003 - Issue 10
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Research Article

Protective Effects of Seabuckthorn Seed Oil on Mouse Injury Induced by Sulfur Dioxide Inhalation

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Pages 1053-1058 | Published online: 01 Oct 2008
 

Abstract

Sulfur dioxide (SO 2) is a common but important air pollutant. Micronuclei (MN) in the polychromatic erythrocytes (PCE) of mouse bone marrow and the ratio between organ and body weight of treatment mouse were determined and analyzed in vivo in order to study injury of sulfur dioxide inhalation on organs and germ plasm of mouse as well as protective effect of seabuckthorn seed oil against this injury. It was showed that SO 2 inhalation induced the change of the ratio between organ and body of mouse organs, such as liver, lung, kidney, and spleen, and a significant increase of number of MNPCE, while seabuckthorn seed oil offered a protection against such injury.

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