I-131 uptake in the breast from fat necrosis

Joseph T. HoangDepartment of Medicine, Texas A&M College of Medicine, Dallas, Texas;

http://orcid.org/0000-0002-2223-3150

, BS

Matthew R. WeissenbornDepartment of Radiology, Baylor University Medical Center at Dallas, Dallas, Texas;

http://orcid.org/0000-0003-4878-1187

, MD

Joseph J. SpigelDepartment of Radiology, Baylor University Medical Center at Dallas, Dallas, Texas;

, MD,

Brian J. WelchDepartment of Internal Medicine, Baylor University Medical Center at Dallas, Dallas, Texas

http://orcid.org/0000-0003-2550-5454

, MD

Stanley J. GrossmanDepartment of Radiology, Baylor University Medical Center at Dallas, Dallas, Texas; Correspondence[email protected]

, MD

Abstract

Radioactive iodine I-131 whole-body scintigraphy is used to monitor thyroid cancer metastases after total thyroidectomy. We present a case of a woman who was diagnosed with papillary thyroid cancer and underwent a total thyroidectomy. I-131 scintigraphy revealed abnormal accumulation of radioactive iodine in the right breast causing concern for thyroid cancer metastasis. Mammographic studies confirmed that the abnormal radiotracer accumulation was due to fat necrosis in the breast. I-131 uptake in fat necrosis is a poorly understood process that is not clearly defined in the literature. This case highlights that false-positive uptake of I-131 can mimic metastases of thyroid carcinoma.

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I-131 uptake in the breast from fat necrosis

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I-131 uptake in the breast from fat necrosis

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