IgA negative immunofluorescence in diagnoses of adult-onset Henoch-Schönlein purpura

Pooja PoudelDepartment of Internal Medicine, State University of New York Upstate Medical University, Syracuse, New York; Correspondence[email protected]

http://orcid.org/0000-0001-7274-7590

, MBBS

Steven H. AdamsState University of New York Upstate Medical University, Syracuse, New York;

http://orcid.org/0000-0002-4866-1305

, BSc

Kanish MirchiaDepartment of Pathology, State University of New York Upstate Medical University, Syracuse, New York;

, MD,

Hanish JainDepartment of Infectious Disease, State University of New York Upstate Medical University, Syracuse, New York

http://orcid.org/0000-0002-2144-9056

, MD

Ambika ErankiDepartment of Infectious Disease, State University of New York Upstate Medical University, Syracuse, New York

, MD

Abstract

We describe two cases of young adult men presenting with diffuse petechial rash and gastrointestinal disturbances. They were found to have leukocytoclastic vasculitis without immunoglobulin A findings under direct immunofluorescence on skin biopsy histopathology performed over a week after the appearance of lesions. Henoch Schönlein purpura (HSP) was diagnosed based upon the clinical presentation as well as the leukocytoclastic vasculitis biopsy findings.

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IgA negative immunofluorescence in diagnoses of adult-onset Henoch-Schönlein purpura

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IgA negative immunofluorescence in diagnoses of adult-onset Henoch-Schönlein purpura

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