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Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 35, 2022 - Issue 3
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Case Studies

“Popper” induced methemoglobinemia

, MD, , MD, , BS & , DO
Pages 385-386 | Received 06 Dec 2021, Accepted 10 Jan 2022, Published online: 02 Feb 2022
 

Abstract

Methemoglobinemia is a blood disorder in which red blood cells contain methemoglobin, a form of hemoglobin that contains iron in its oxidized state, at levels >1%, often leading to a hypoxic state. It can be acquired or congenital and has been associated with nitrate or nitrite exposure. “Poppers” and “Rush” are slang terms given to drugs of the chemical class called amyl nitrate or isobutyl nitrite, which are typically inhaled and can be found over the counter. They are used with the intention of enhancing sexual performance due to their vasodilator effects, anal sphincter relaxation, and aphrodisia. We report a case of a man who developed methemoglobinemia secondary to “popper” abuse.

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