Successful treatment of sclerosing mesenteritis with tamoxifen monotherapy

Abstract

Sclerosing mesenteritis is a rare disorder characterized by fat necrosis, chronic inflammation, and fibrosis of the small bowel mesentery. With a paucity of published clinical trials on sclerosing mesenteritis, treatment is based on case reports and trials of other fibrosing diseases, such as idiopathic retroperitoneal fibrosis. We present a case of a 68-year-old woman with sclerosing mesenteritis who exhibited complete symptomatic and radiographic resolution with the use of tamoxifen monotherapy.

Keywords:

• Retroperitoneal fibrosis
• sclerosing mesenteritis
• tamoxifen

Disclosure statement/Funding

The authors report no funding or conflicts of interest. Permission for publication of this case was granted by the patient’s representative.