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Food & Nutrition Science (Notes)

The enhancing effect of fucoidan derived from Undaria pinnatifida on immunoglobulin production by mouse spleen lymphocytes

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Pages 1743-1747 | Received 05 Feb 2014, Accepted 19 Apr 2014, Published online: 26 Jun 2014
 

Abstract

In this study, we revealed that a Mekabu (Udaria pinnantifida) extract enhanced immunoglobulin (Ig) production of mouse spleen lymphocytes. Furthermore, it was suggested that water-soluble and high molecular weight ingredients in the Mekabu extract have significant enhancing effect on Ig production. Therefore, fucoidan was estimated as the active component.

Notes

Abbreviations: Ig, immunoglobulin; ELISA, enzyme-linked immunosorbent assay; MW, molecular weight; LMWF, low molecular weight fractions; HMWF, high molecular weight fractions.

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