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Abstract
Effects of the administration of maple syrup extract (MSX) on hepatic gene expression were investigated in mice fed a high-fat diet. Gene annotation enrichment analysis based on gene ontology revealed some changes in the expression of genes related to lipid metabolism and the immune response in MSX-fed mice. Detailed analysis of these data indicated that MSX ingestion mitigates hepatic inflammation.
Disclosure statement
All the authors do not have any potential conflict of interest.
Notes
Abbreviations: MSX, maple syrup extract; qFARMS, Factor Analysis for Robust Microarray Summarization; FDR, false discovery rate; RP, rank products; KEGG, Kyoto Encyclopedia of Genes and Genomes; GO, gene ontology.
Additional information
Funding
This project was supported by Ministère de l’Agriculture, des Pêcheries et de l’Alimentation of Quebec (MAPAQ) through the “Soutien aux strategies sectorielles de développement Volet 1: Appui au développement sectorial” program with the participation of the Federation of Quebec Maple Syrup Producers (FPAQ); Council for Science, Technology and Innovation (CSTI), Cross-ministerial Strategic Innovation Promotion Program (SIP), “Technologies for creating next-generation agriculture, forestry and fisheries”; Regional Innovation Strategy Support Program.