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Abstract
Lactococcus lactis subsp. lactis JCM 5805 (JCM5805) has been shown to stimulate plasmacytoid dendritic cells (pDC). Here, we investigated the effect of JCM5805 on NK cells. In vitro studies suggested that JCM5805 activated natural killer (NK) cells via dendritic cells including pDC. Furthermore, the oral administration of JCM5805 enhanced the cytotoxic activity of NK cells
Notes
Abbreviations: JCM5805, Lactococcus lactis subsp. lactis JCM 5805; pDC, plasmacytoid dendritic cells; I-IFN, Type I Interferones; TLR9, Toll-like Receptor 9; LAB, lactic acid bacteria; mDC, myeloid dendritic cells; BM-DC, bone-marrow derived DC; PP, Peyer’s patches.