Abstract
In crustaceans, various physiological events, such as molting, vitellogenesis, and sex differentiation, are regulated by peptide hormones. To understanding the functional sites of these hormones, many structure–activity relationship (SAR) studies have been published. In this review, the author focuses the SAR of crustacean hyperglycemic hormone-family peptides and androgenic gland hormone and describes the detailed results of our and other research groups. The future perspectives will be also discussed.
Graphical abstract
In this review, the author outlines the results of structure–activity relationship studies on crustacean peptide hormones by our and the other research groups.
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Acknowledgments
I would like to express my sincere thanks to my supervisors, Prof. Hiromichi Nagasawa of the University of Tokyo, Prof. Saburo Aimoto of Osaka University, Prof. J. Sook Chung of University of Maryland Biotechnology Institute, and Prof. Hironobu Hojo of Osaka University. I am also grateful to my all collaborators, especially Profs. Katsumi Aida, Masaru Tanokura, Yoshiaki Nakahara, Haruyuki Sonobe, Osamu Nureki, Akemi Suzuki, Drs. Shohei Sakuda, Jiro Nakayama, Koji Nagata, Shinji Nagata, Toru Kawakami, Tsuyoshi Ohira, Naoaki Tsutsui, Yuko Nakahara, and Fumiaki Yumoto. Finally, I thank the committee members of The Japan Bioscience, Biotechnology, and Agrochemistry Society for their nomination for the Young Scientists Award in 2015.
Disclosure statement
No potential conflict of interest was reported by the author.
Funding
This work was supported in part by Grants-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology of Japan, Grant-in-Aid from Kato Memorial Foundation; Research and Study Program of Tokai University Educational System General Research Organization.
Notes
This review was written in response to the author’s receipt of the JSBBA Award for Young Scientists in 2015.