ABSTRACT
N6-Isopentenyladenosine (i6A) was isolated from a marine sponge Oceanapia sp. as the major cytotoxic constituent along with N6-isopentenyladenosine 5ʹ-monophosphate (i6AP) which was inactive. The structures of i6A and i6AP were assigned by a combination of the analysis of NMR spectroscopy and mass spectrometry. This is the first isolation of i6A and i6AP from a marine sponge.
Acknowledgments
We thank the captain and crew of the T/S Toyoshio-maru for sample collection.
Author contribution
SN isolated and identified the compounds and wrote the draft of the manuscript. YI identified the sponge. SOh conducted the collection of the sponge. SOk participated to design the study. SM designed the study and prepared the manuscript. All authors reviewed and approved the final manuscript.
Disclosure statement
No potential conflict of interest was reported by the authors.
Supplementary material
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