Effective preparation of magnetic molecularly imprinted polymer nanoparticle for the rapid and selective extraction of cyfluthrin from honeysuckle

Abstract

Cyfluthrin is a widely used pesticide. In this study, a sensitive and efficient magnetic molecularly imprinted polymer (MMIP) was prepared by surface molecular imprinting, which used functionalized Fe₃O₄ particles as magnetic cores. Cyfluthrin was extracted and enriched using magnetic molecularly polymer for analyzing pesticide residue of Chinese herbal medicines. The crystal type, microstructure, particle size, saturation magnetization, and characteristic functional groups of the synthesized MMIPs were analyzed by analysis equipment. The results of isothermal adsorption and kinetic adsorption indicated that MMIPs reached adsorption equilibrium at 30 min, with a maximum capacity of 4.9 mg g⁻¹, which had good adsorption performance, while selective adsorption experiments showed that MMIPs had higher affinity for cyfluthrin. Under the optimized conditions, the limit of detection (LOD) and the limit of quantification (LOQ) were 32.987 ng ml⁻¹ and 109.955 ng ml⁻¹, respectively. And linear range (30–3000ng ml⁻¹) of cyfluthrin with correlation coefficient R²=0.9979, and MMIPs were used in honeysuckle, the recoveries were 91.5%∼97.2%, and RSD was 5.35%∼8.32% (n = 3). It is indicated that the magnetic molecularly imprinted polymer can be used as an effective material for the specific separation of cyfluthrin from honeysuckle.

Keywords:

• Magnetic molecularly imprinted
• cyfluthrin
• molecular recognition
• honeysuckle
• HPLC

Acknowledgments

The project was financially supported by the National Natural Science Foundation of China (No. 31660437), Major Projects of Yunnan Provincial Science and Technology Department (No. 2018ZF004) and China Agriculture Research System (CARS-21).

Disclosure statement

No potential conflict of interest was reported by the author(s).