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Research Article

Biocompatible and photocrosslinkable poly(ethylene glycol)/keratin biocomposite hydrogels

, , , & ORCID Icon
Pages 1998-2008 | Received 11 May 2021, Accepted 03 Jul 2021, Published online: 28 Jul 2021
 

Abstract

A biocompatible hydrogel is ideal for tissue engineering and regeneration. In this study, methacrylated keratin (KerMA) was synthesized for the first time and then blended with poly(ethylene glycol dimethacrylate) (PEGDMA) to form hydrogel through photocrosslinking. The chemical structure, gelation time, swelling behavior, hydrophilicity, cytotoxicity, and 3D printability of PEGDMA/KerMA hydrogels were characterized and exploited. The PEGDMA/KerMA hydrogels performed good cytocompatibility, providing potential applications for tissue engineering and regenerative medicine.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by Jiangsu Higher Education Institutions [19KJA310001 and PAPD].

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