Abstract
Purpose: To report a case of a pseudo-hypopyon as the presentation for recurrent B-cell lymphoma. Design: Case report. Methods: Case report with anterior segment photograph. Results: A 74-year-old man with past medical history of peripheral B-cell lymphoma developed a hypopyon 3 months after R-CHOP chemotherapy and prophylactic intrathecal chemotherapy. Anterior chamber aspirate was consistent with B-cell lymphoma. Conclusions: Pseudo-hypopyon as a manifestation of recurrent B-cell lymphoma is a rare clinical presentation of an intraocular malignancy. A high index of suspicion along with intraocular fluid analysis are essential to establish the diagnosis.